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TickerAMGN
SectorDrug Manufacturers - General
Mkt cap$179B
EV / EBITDA12.9×
PostureHigh Velocity
Composite78/100
LensBuyer-side
SE-Cluster Research·Issuer Brief·Q2 2026CIK 318154

Amgen Inc.

AMGNHIGH VELOCITYDEAL MODE DOMINANT

Amgen Inc. reads as an High Velocity (composite 78/100); Transformational Buyer deploying $27B across 1 disclosed transactions, up 446% vs the prior cycle · primary market Healthcare, ranked #4 on disclosed spend.

Lens

Disclosed M&A capital (2023–2025)

$26.7B

+446%

vs $4.9B in 2020–2022

Disclosed transactions

1

flat

1/3 active fiscal years in window

Buyer archetype

Transformational Buyer

Episodic but very large disclosed transactions drive the profile.

Composite score

78

/100

High Velocity dominates · Deal Mode Dominant

Financial snapshot
Revenue$37.2B
EBITDA$17.3B
Enterprise value$224.3B
EV / Revenue6.0×
EV / EBITDA12.9×
P/EN/A
Cash$12B
Total debt$57.3B
as of 2026-05-10
§ I·SE-Cluster Issuer Brief

Behavioral posture, nine reads.

Each index scores the issuer 0–100 against an EDGAR-anchored definition. Scores ≥ threshold elevate the issuer into the index's constituent set; the dominant index drives the masthead label.

Active Acquirer

62/100

Companies actively deploying disclosed capital into M&A

  • $120.4B disclosed buyer spend
  • Filed within 25d

Buyer Cadence

32/100

Buyer-side companies with recent filing activity

  • Filed within 25d
  • 321 8-Ks

Target Probability

24/100

Issuers showing target-side patterns from filings

  • 31 activism filings

Spin/Carve

0/100

Issuers showing spin-off, carve-out, or sum-of-parts posture

  • 31 activism filings

Pressure Watch

45/100

Issuers facing activism, governance, or control pressure

  • 31 activism filings
  • Latest activism 2.7y ago; discounted

Distress Watch

18/100

Issuers showing financial-distress filing patterns

  • 31 activism filings

Restatement Risk

0/100

Issuers with accounting-integrity flags from filings

Capital Velocity

Dominant
78/100

Issuers with the highest filing-activity intensity

  • 321 8-Ks
  • Filed within 25d
  • 5 form types

Quiet Power

0/100

Large issuers with low signal volume and clean disclosure cadence

  • Enterprise value $224.3B
  • 10-Q 25d ago
  • 2 active signals
§ II·SE-Cluster Issuer Brief

Capital cadence.

Ten-year disclosed M&A activity. Bars show spend ($MM); ticks show recorded transaction count. Disclosure tier annotated where v6 audited corpus carries an entry.

16
17
18
19
20
21
22
23
24
25

Disclosed spend $MM Disclosed transactions (right axis)Peak spend year: $26,700M · Peak count: 2

FYDisclosed buysDisclosed spendAvg ticketAudited tier
2025N/AN/AN/AN/A
2024N/AN/AN/AN/A
20231$26.7B$26.7BN/A
20221$3.9B$3.9BN/A
2021N/A$994MN/AN/A
2020N/AN/AN/AN/A
§ III·SE-Cluster Issuer Brief

Strategy posture.

The buyer's playbook in terms of strategic archetype: what each disclosed move says about how they're deploying capital.

Archetype mix

  • Platform
    25%
  • Geographic Expansion
    25%
  • Bolt On
    25%
  • Technology Acquisition
    25%

Strategy keywords

Terms recurring across recent 10-K acquisition disclosures.

  • platform
  • geographic_expansion
  • bolt_on
  • technology_acquisition
§ IV·SE-Cluster Issuer Brief

Filing language.

Direct excerpts from acquisition disclosures and strategy sections: the verbs the buyer chose, in the filings they signed.

In the U.S. private sector, healthcare providers and payers continue to institute cost reduction and containment measures that lower drug spending altogether or shift a greater portion of the costs to patients.

10-KFY2016

acquired all of the outstanding stock of Nuevolution AB, a publicly traded, Denmark-based biotechnology company with a leading small molecule drug discovery platform

10-KFY2019

PBMs are third-party organizations tasked with administrating prescription drug programs for large employers, health plans and government programs.

10-KFY2016

This transaction, which was accounted for as a business combination, provides us with an opportunity to expand our oncology franchise.

10-KFY2013

we acquired worldwide rights to Otezla®, the only oral, non-biologic treatment for psoriasis and psoriatic arthritis

10-KFY2019
§ V·SE-Cluster Issuer Brief

Market context.

Where this issuer sits inside its SE-Cluster rollup wedge, with disclosed-spend rank plus trading comparables against the public peer set.

Primary market

Healthcare

Market spend (2023–2025)
$195B
Market spend (2020–2022)
$253.6B
Recent vs prior
−23%
Issuer rank in market
#4 of 391
Share of market capital
7.1%

Valuation positioning

12.9×EV / EBITDA

AMGN trades at a -2.1-turn discount to the Healthcare peer median of 15.0×.

EV / Revenue
6.0×
Net debt / EBITDA
2.6×
Peer median EV / EBITDA
15.0×

Trading comparables

FMP market data · 2026-05-10

CompanyEV / EBITDAEV / RevNet debt / EBITDARevenueM&A 2023–2025
23.4×6.7×3.1×$62.8B$18B
17.2×0.9×1.9×$449.7B$28.1B
15.0×5.1×1.2×$60.4B$19M
Amgen Inc.AMGN
12.9×6.0×2.6×$37.2B$26.7B
11.7×0.5×2.5×$200.4B$6.4B
9.3×1.9×2.8×$76.4B$1.3B

Trading multiples from FMP market data; disclosed M&A spend from the SE-Cluster EDGAR 10-K corpus. Peer set = top disclosed buyers in Healthcare. Bars scaled to the highest EV/EBITDA in the set.

§ VI·SE-Cluster Issuer Brief

Target landscape.

Public-issuer targets that fit this buyer's archetype and target categories from filing-derived signal. Scores reflect cross-signal fit; reasons cite the EDGAR-anchored facts that drove the match.

No qualifying public-issuer targets surfaced from the current signal mix.

Stated target categories

No target categories enumerated in the audited corpus for this issuer.

§ VII·SE-Cluster Issuer Brief

Filing activity & signal stream.

Filing cadence and event-driven signals visible on EDGAR. The signal stream below is curated from restatement / spin-carve / activism categories, providing context for any near-term call.

Filing cadence

  • 10-K (annual)342026-02-13
  • 10-Q (quarterly)1012026-05-01
  • 8-K (event)3212026-04-30
  • Proxy / DEF 14A1072026-04-21
  • Activism (13D / DFAN / PREC)312023-09-27

Signals on file

  • elevated

    Activism on file

    2023-09-27

    31 activist filings on file (13D, DFAN14A, PREC14A series).

  • info

    Signal

    Serial acquisition history

  • info

    Signal

    10-K strategy themes

§ VIII·SE-Cluster Issuer Brief

Audited corpus.

No audited record on file for this CIK in the current v6 corpus.

This issuer has not been extracted into the v6 audited acquirer corpus yet. The brief above pulls from ranking-level aggregates and issuer-index signal only.

Amgen Inc.: Issuer Brief | SE-Cluster