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TickerAYTU
SectorDrug Manufacturers - Specialty & Generic
Mkt cap$20M
EV / EBITDAN/A
PostureHigh Velocity
Composite62/100
LensTarget-side
SE-Cluster Research·Issuer Brief·Q2 2026CIK 1385818

Aytu Biopharma, Inc.

AYTUHIGH VELOCITYFILING INTENSITY

Aytu Biopharma, Inc. reads as High Velocity (composite 62/100); pressure / disclosure signals dominate the posture this cycle · primary market Healthcare.

Lens

Disclosed M&A capital (2023–2025)

N/A

−99%

vs N/A in 2020–2022

Disclosed transactions

N/A

−99%

0/3 active fiscal years in window

Buyer archetype

Consistent Strategic Buyer

Meaningful spend appears across repeat years.

Composite score

62

/100

High Velocity dominates · Filing Intensity

Financial snapshot
Revenue$63M
EBITDAN/A
Enterprise value$13M
EV / Revenue0.2×
EV / EBITDAN/A
P/EN/A
Cash$30M
Total debt$2M
as of 2026-05-10
§ I·SE-Cluster Issuer Brief

Behavioral posture, nine reads.

Each index scores the issuer 0–100 against an EDGAR-anchored definition. Scores ≥ threshold elevate the issuer into the index's constituent set; the dominant index drives the masthead label.

Active Acquirer

37/100

Companies actively deploying disclosed capital into M&A

  • $4.5B disclosed buyer spend

Buyer Cadence

3/100

Buyer-side companies with recent filing activity

  • 230 8-Ks

Target Probability

18/100

Issuers showing target-side patterns from filings

  • 16 activism filings

Spin/Carve

0/100

Issuers showing spin-off, carve-out, or sum-of-parts posture

  • 16 activism filings

Pressure Watch

47/100

Issuers facing activism, governance, or control pressure

  • 16 activism filings
  • Latest activism 2y ago

Distress Watch

30/100

Issuers showing financial-distress filing patterns

  • 16 activism filings

Restatement Risk

52/100

Issuers with accounting-integrity flags from filings

  • 1 non-reliance 8-K
  • 3 auditor changes
  • 4 NT late filings
  • Latest event 2.7y ago; discounted

Capital Velocity

Dominant
62/100

Issuers with the highest filing-activity intensity

  • 230 8-Ks
  • 5 form types

Quiet Power

0/100

Large issuers with low signal volume and clean disclosure cadence

  • Enterprise value $13M
  • 10-Q 126d ago
  • 2 active signals
§ II·SE-Cluster Issuer Brief

Capital cadence.

Ten-year disclosed M&A activity. Bars show spend ($MM); ticks show recorded transaction count. Disclosure tier annotated where v6 audited corpus carries an entry.

16
17
18
19
20
21
22
23
24
25

Disclosed spend $MM Disclosed transactions (right axis)Peak spend year: $4,500M · Peak count: 2

FYDisclosed buysDisclosed spendAvg ticketAudited tier
2025N/AN/AN/AN/A
2024N/AN/AN/AN/A
2023N/AN/AN/AN/A
2022N/AN/AN/AN/A
20212$18M$9MN/A
20202$4.5B$2.3BN/A
§ IV·SE-Cluster Issuer Brief

Filing language.

Direct excerpts from acquisition disclosures and strategy sections: the verbs the buyer chose, in the filings they signed.

the acquisition of us by another entity by means of any transaction or series of related transactions to which we are party (including, without limitation, any stock acquisition, reorganization, merger or consolidation but excluding any issuance of securities by us in a transaction or series of transactions made principally for bona fide equity financing purposes) other than a transaction or series of related transactions in which the holders of the voting securities of us outstanding immediately prior to such transaction or series of related transactions retain, immediately after such transaction or series of related transactions, as a result of shares in us held by such holders prior to such transaction or series of related transactions, at least a majority of the total voting power represented by the outstanding voting securities of us or such other surviving or resulting entity (or if we or such other surviving or resulting entity is a wholly-owned subsidiary immediately following such acquisition, its parent);

10-KFY2019

integration of our acquisitions and the commercialization of our product pipeline

10-KFY2023

reductions of redundancies from the Neos and Innovus acquisitions

10-KFY2023
§ V·SE-Cluster Issuer Brief

Market context.

Where this issuer sits inside its SE-Cluster rollup wedge, with disclosed-spend rank plus trading comparables against the public peer set.

Primary market

Healthcare

Market spend (2023–2025)
$195B
Market spend (2020–2022)
$253.6B
Recent vs prior
−23%
Issuer rank in market
N/A
Share of market capital
0.0%

Valuation positioning

N/AEV / EBITDA

AYTU trades at a -13.7-turn discount to the Healthcare peer median of 12.9×.

EV / Revenue
0.2×
Net debt / EBITDA
N/A
Peer median EV / EBITDA
12.9×

Trading comparables

FMP market data · 2026-05-10

CompanyEV / EBITDAEV / RevNet debt / EBITDARevenueM&A 2023–2025
23.4×6.7×3.1×$62.8B$18B
17.2×0.9×1.9×$449.7B$28.1B
12.9×6.0×2.6×$37.2B$26.7B
11.7×0.5×2.5×$200.4B$6.4B
9.3×1.9×2.8×$76.4B$1.3B

Trading multiples from FMP market data; disclosed M&A spend from the SE-Cluster EDGAR 10-K corpus. Peer set = top disclosed buyers in Healthcare. Bars scaled to the highest EV/EBITDA in the set.

§ VI·SE-Cluster Issuer Brief

Buyer landscape.

Public buyers whose stated archetypes, target categories, and recent cadence align with this issuer as a plausible acquisition target. Scores cross EDGAR signal and disclosure overlap.

Likely buyers

No public buyers surface as a strong target-side fit on current signal.

Likely sellers / divestiture partners

No reciprocal divestiture / strategic-alternatives matches identified.

§ VII·SE-Cluster Issuer Brief

Filing activity & signal stream.

Filing cadence and event-driven signals visible on EDGAR. The signal stream below is curated from restatement / spin-carve / activism categories, providing context for any near-term call.

Filing cadence

  • 10-K (annual)212025-09-23
  • 10-Q (quarterly)552026-02-03
  • 8-K (event)2302026-04-02
  • Proxy / DEF 14A302025-10-24
  • Activism (13D / DFAN / PREC)162024-06-18

Signals on file

  • critical

    Non-reliance disclosure

    2023-02-21

    1 Item 4.02 filing on file; financial-statement non-reliance.

  • elevated

    Auditor change

    2022-12-13

    3 Item 4.01 filings on file; certifying accountant change.

  • watch

    Late-filing notice

    2023-09-29

    4 NT 10-K/10-Q filings on file.

  • elevated

    Activism on file

    2024-06-18

    16 activist filings on file (13D, DFAN14A, PREC14A series).

  • info

    Signal

    Serial acquisition history

  • info

    Signal

    Restatement risk

§ VIII·SE-Cluster Issuer Brief

Audited corpus.

No audited record on file for this CIK in the current v6 corpus.

This issuer has not been extracted into the v6 audited acquirer corpus yet. The brief above pulls from ranking-level aggregates and issuer-index signal only.