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TickerWGS
SectorMedical - Healthcare Information Services
Mkt cap$1.2B
EV / EBITDAN/A
PostureHigh Velocity
Composite70/100
LensTarget-side
SE-Cluster Research·Issuer Brief·Q2 2026CIK 1818331

GeneDx Holdings Corp.

WGSHIGH VELOCITYFILING INTENSITY

GeneDx Holdings Corp. reads as High Velocity (composite 70/100); pressure / disclosure signals dominate the posture this cycle · primary market Marketing & Data.

Lens

Disclosed M&A capital (2023–2025)

$45M

−93%

vs $651M in 2020–2022

Disclosed transactions

2

flat

2/3 active fiscal years in window

Buyer archetype

Selective Buyer

Acquisition use is visible but targeted.

Composite score

70

/100

High Velocity dominates · Filing Intensity

Financial snapshot
Revenue$443M
EBITDAN/A
Enterprise value$1.3B
EV / Revenue2.9×
EV / EBITDAN/A
P/EN/A
Cash$94M
Total debt$100M
as of 2026-05-10
§ I·SE-Cluster Issuer Brief

Behavioral posture, nine reads.

Each index scores the issuer 0–100 against an EDGAR-anchored definition. Scores ≥ threshold elevate the issuer into the index's constituent set; the dominant index drives the masthead label.

Active Acquirer

27/100

Companies actively deploying disclosed capital into M&A

  • $696M disclosed buyer spend

Buyer Cadence

15/100

Buyer-side companies with recent filing activity

  • Filed within 36d
  • 63 8-Ks

Target Probability

20/100

Issuers showing target-side patterns from filings

  • 28 activism filings

Spin/Carve

0/100

Issuers showing spin-off, carve-out, or sum-of-parts posture

  • 28 activism filings

Pressure Watch

49/100

Issuers facing activism, governance, or control pressure

  • 28 activism filings
  • Latest activism 1.6y ago

Distress Watch

18/100

Issuers showing financial-distress filing patterns

  • 28 activism filings

Restatement Risk

50/100

Issuers with accounting-integrity flags from filings

  • 3 non-reliance 8-Ks
  • 2 auditor changes
  • 1 NT late filing
  • Latest event 4.2y ago; discounted

Capital Velocity

Dominant
70/100

Issuers with the highest filing-activity intensity

  • 63 8-Ks
  • 5 form types

Quiet Power

0/100

Large issuers with low signal volume and clean disclosure cadence

  • Enterprise value $1.3B
  • 10-Q 36d ago
  • 3 active signals
§ II·SE-Cluster Issuer Brief

Capital cadence.

Ten-year disclosed M&A activity. Bars show spend ($MM); ticks show recorded transaction count. Disclosure tier annotated where v6 audited corpus carries an entry.

16
17
18
19
20
21
22
23
24
25

Disclosed spend $MM Disclosed transactions (right axis)Peak spend year: $510M · Peak count: 1

FYDisclosed buysDisclosed spendAvg ticketAudited tier
20251$33M$33MN/A
2024N/AN/AN/AN/A
20231$12M$12MN/A
20221$141M$141MN/A
20211$510M$510MN/A
2020N/AN/AN/AN/A
§ III·SE-Cluster Issuer Brief

Strategy posture.

The buyer's playbook in terms of strategic archetype: what each disclosed move says about how they're deploying capital.

Archetype mix

  • Platform
    25%
  • Bolt On
    25%
  • Geographic Expansion
    25%
  • Technology Acquisition
    25%

Strategy keywords

Terms recurring across recent 10-K acquisition disclosures.

  • platform
  • bolt_on
  • geographic_expansion
  • technology_acquisition
§ IV·SE-Cluster Issuer Brief

Filing language.

Direct excerpts from acquisition disclosures and strategy sections: the verbs the buyer chose, in the filings they signed.

Consistent with our acquisition strategy, we have identified the following criteria to evaluate prospective target businesses. We intend to seek to acquire companies in the Life Sciences Tools, Synthetic Biology and Diagnostics fields and that we believe:

10-KFY2020

Centrellis® integrates digital tools and artificial intelligence, allowing our scientists to ingest and synthesize clinical and genomic data to deliver better, more comprehensive health insights.

10-KFY2022

GeneDx was acquired by and integrated with Sema4 Holdings, adding Legacy Sema4’s Centrellis®, a highly innovative health information platform to our portfolio of solutions.

10-KFY2022

we continue to use the proceeds from our July 2021 business combination and related private placement financing to accelerate growth

10-KFY2021

we intend to apply capital over time to make targeted acquisitions to accelerate our ability to reach a wider range of patients

10-KFY2021
§ V·SE-Cluster Issuer Brief

Market context.

Where this issuer sits inside its SE-Cluster rollup wedge, with disclosed-spend rank plus trading comparables against the public peer set.

Primary market

Marketing & Data

Market spend (2023–2025)
$51.4B
Market spend (2020–2022)
$63.5B
Recent vs prior
−19%
Issuer rank in market
N/A
Share of market capital
0.0%

Valuation positioning

Trading comparables unavailable for this wedge.

§ VI·SE-Cluster Issuer Brief

Buyer landscape.

Public buyers whose stated archetypes, target categories, and recent cadence align with this issuer as a plausible acquisition target. Scores cross EDGAR signal and disclosure overlap.

Likely buyers

No public buyers surface as a strong target-side fit on current signal.

Likely sellers / divestiture partners

No reciprocal divestiture / strategic-alternatives matches identified.

§ VII·SE-Cluster Issuer Brief

Filing activity & signal stream.

Filing cadence and event-driven signals visible on EDGAR. The signal stream below is curated from restatement / spin-carve / activism categories, providing context for any near-term call.

Filing cadence

  • 10-K (annual)72026-02-23
  • 10-Q (quarterly)172026-05-04
  • 8-K (event)632026-05-04
  • Proxy / DEF 14A272026-04-30
  • Activism (13D / DFAN / PREC)282024-11-20

Signals on file

  • critical

    Non-reliance disclosure

    2022-03-14

    3 Item 4.02 filings on file; financial-statement non-reliance.

  • elevated

    Auditor change

    2021-08-16

    2 Item 4.01 filings on file; certifying accountant change.

  • watch

    Late-filing notice

    2021-05-18

    1 NT 10-K/10-Q filing on file.

  • elevated

    Activism on file

    2024-11-20

    28 activist filings on file (13D, DFAN14A, PREC14A series).

  • info

    Signal

    Serial acquisition history

  • info

    Signal

    10-K strategy themes

  • info

    Signal

    Restatement risk

§ VIII·SE-Cluster Issuer Brief

Audited corpus.

No audited record on file for this CIK in the current v6 corpus.

This issuer has not been extracted into the v6 audited acquirer corpus yet. The brief above pulls from ranking-level aggregates and issuer-index signal only.