SE‑Cluster

Search

Search markets, companies, evidence, and pages

TickerPEN
SectorMedical - Devices
Mkt cap$12.7B
EV / EBITDA59.5×
PostureHigh Velocity
Composite70/100
LensTarget-side
SE-Cluster Research·Issuer Brief·Q2 2026CIK 1321732

Penumbra, Inc

PENHIGH VELOCITYFILING INTENSITY

Penumbra, Inc reads as High Velocity (composite 70/100); pressure / disclosure signals dominate the posture this cycle · primary market Life Sciences.

Lens

Disclosed M&A capital (2023–2025)

$251M

−50%

vs $502M in 2020–2022

Disclosed transactions

N/A

−99%

1/3 active fiscal years in window

Buyer archetype

Consistent Strategic Buyer

Meaningful spend appears across repeat years.

Composite score

70

/100

High Velocity dominates · Filing Intensity

Financial snapshot
Revenue$1.5B
EBITDA$213M
Enterprise value$12.6B
EV / Revenue8.7×
EV / EBITDA59.5×
P/EN/A
Cash$241M
Total debtN/A
as of 2026-05-10
§ I·SE-Cluster Issuer Brief

Behavioral posture, nine reads.

Each index scores the issuer 0–100 against an EDGAR-anchored definition. Scores ≥ threshold elevate the issuer into the index's constituent set; the dominant index drives the masthead label.

Active Acquirer

27/100

Companies actively deploying disclosed capital into M&A

  • $803M disclosed buyer spend

Buyer Cadence

14/100

Buyer-side companies with recent filing activity

  • Filed within 33d
  • 90 8-Ks

Target Probability

32/100

Issuers showing target-side patterns from filings

  • Control-process language

Spin/Carve

0/100

Issuers showing spin-off, carve-out, or sum-of-parts posture

Pressure Watch

25/100

Issuers facing activism, governance, or control pressure

  • Control-process filings

Distress Watch

0/100

Issuers showing financial-distress filing patterns

Restatement Risk

5/100

Issuers with accounting-integrity flags from filings

  • 1 auditor change
  • Latest event 2.2y ago; discounted

Capital Velocity

Dominant
70/100

Issuers with the highest filing-activity intensity

  • 90 8-Ks
  • 4 form types

Quiet Power

0/100

Large issuers with low signal volume and clean disclosure cadence

  • Enterprise value $12.6B
  • 10-Q 34d ago
  • 5 active signals
§ II·SE-Cluster Issuer Brief

Capital cadence.

Ten-year disclosed M&A activity. Bars show spend ($MM); ticks show recorded transaction count. Disclosure tier annotated where v6 audited corpus carries an entry.

16
17
18
19
20
21
22
23
24
25

Disclosed spend $MM Disclosed transactions (right axis)Peak spend year: $251M · Peak count: 1

FYDisclosed buysDisclosed spendAvg ticketAudited tier
2025N/AN/AN/AN/A
2024N/AN/AN/AN/A
2023N/A$251MN/AN/A
2022N/A$251MN/AN/A
20211$251M$251MN/A
2020N/AN/AN/AN/A
§ III·SE-Cluster Issuer Brief

Strategy posture.

The buyer's playbook in terms of strategic archetype: what each disclosed move says about how they're deploying capital.

Archetype mix

  • Bolt On
    33%
  • Geographic Expansion
    33%
  • Technology Acquisition
    33%

Strategy keywords

Terms recurring across recent 10-K acquisition disclosures.

  • bolt_on
  • geographic_expansion
  • technology_acquisition
§ IV·SE-Cluster Issuer Brief

Filing language.

Direct excerpts from acquisition disclosures and strategy sections: the verbs the buyer chose, in the filings they signed.

We had commissioned and subsequently evaluated the Penumbra System in our THERAPY study, a clinical study comparing the clinical outcomes in the medical management of stroke patients with IV recombinant tPA (rtPA) to stroke patients treated with a combination of IV rtPA and the Penumbra System. The THERAPY study was commenced in March 2012, and was designed to enroll up to 692 patients, but was stopped early in October 2014, because the positive results of the MR CLEAN study made it unethical to continue to treat the control group in the THERAPY study with medical management rather than with endovascular treatment. The MR CLEAN study demonstrated the superiority of endovascular treatment of stroke over medical management. As a result, the steering committee for THERAPY recommended stopping enrollment for the trial. The THERAPY study results, after the randomization of 108 patients, were presented in April 2015 at the European Stroke Organization Conference and the manuscript is being prepared for submission to a peer-reviewed journal. Despite the early termination of the study, the pre-specified per protocol analysis demonstrated a significant benefit of combined treatment with IV rtPA and the Penumbra System over IV rtPA alone.

10-KFY2015
§ V·SE-Cluster Issuer Brief

Market context.

Where this issuer sits inside its SE-Cluster rollup wedge, with disclosed-spend rank plus trading comparables against the public peer set.

Primary market

Life Sciences

Market spend (2023–2025)
$68.3B
Market spend (2020–2022)
$107.5B
Recent vs prior
−36%
Issuer rank in market
N/A
Share of market capital
0.0%

Valuation positioning

59.5×EV / EBITDA

PEN trades at a +43.4-turn premium to the Life Sciences peer median of 16.1×.

EV / Revenue
8.7×
Net debt / EBITDA
N/A
Peer median EV / EBITDA
16.1×

Trading comparables

FMP market data · 2026-05-10

CompanyEV / EBITDAEV / RevNet debt / EBITDARevenueM&A 2023–2025
Penumbra, IncPEN
59.5×8.7×N/A$1.5B$251M
19.1×4.7×-0.0×$45.2B$10.8B
18.8×4.3×-0.3×$20.6B$8B
13.3×3.5×-0.1×$35.5B$2.2B
13.1×1.9×-0.2×$14.1B$2.1B

Trading multiples from FMP market data; disclosed M&A spend from the SE-Cluster EDGAR 10-K corpus. Peer set = top disclosed buyers in Life Sciences. Bars scaled to the highest EV/EBITDA in the set.

§ VI·SE-Cluster Issuer Brief

Buyer landscape.

Public buyers whose stated archetypes, target categories, and recent cadence align with this issuer as a plausible acquisition target. Scores cross EDGAR signal and disclosure overlap.

Likely buyers

No public buyers surface as a strong target-side fit on current signal.

Likely sellers / divestiture partners

No reciprocal divestiture / strategic-alternatives matches identified.

§ VII·SE-Cluster Issuer Brief

Filing activity & signal stream.

Filing cadence and event-driven signals visible on EDGAR. The signal stream below is curated from restatement / spin-carve / activism categories, providing context for any near-term call.

Filing cadence

  • 10-K (annual)112026-02-25
  • 10-Q (quarterly)332026-05-06
  • 8-K (event)902026-05-07
  • Proxy / DEF 14A232026-04-29
  • Activism (13D / DFAN / PREC)0N/A

Signals on file

  • elevated

    Auditor change

    2024-03-21

    1 Item 4.01 filing on file; certifying accountant change.

  • info

    Signal

    Serial acquisition history

  • info

    Signal

    10-K strategy themes

  • info

    Signal

    Recent transaction activity

§ VIII·SE-Cluster Issuer Brief

Audited corpus.

No audited record on file for this CIK in the current v6 corpus.

This issuer has not been extracted into the v6 audited acquirer corpus yet. The brief above pulls from ranking-level aggregates and issuer-index signal only.

Penumbra, Inc: Issuer Brief | SE-Cluster